Johannes Backs Selected Research

Small Interfering RNA (siRNA)

1/2020

Secretome Analysis of Cardiomyocytes Identifies PCSK6 (Proprotein Convertase Subtilisin/Kexin Type 6) as a Novel Player in Cardiac Remodeling After Myocardial Infarction.

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Johannes Backs Research Topics

Disease

34	Heart Failure 01/2022 - 01/2006
10	Cardiomegaly (Heart Hypertrophy) 01/2022 - 01/2006
9	Hypertrophy 01/2017 - 05/2006
5	Cardiomyopathies (Cardiomyopathy) 01/2022 - 12/2012
4	Neoplasms (Cancer) 10/2020 - 02/2016
4	Fibrosis (Cirrhosis) 01/2020 - 01/2014
3	Cardiac Arrhythmias (Arrythmia) 01/2022 - 11/2009
3	Inflammation (Inflammations) 01/2022 - 12/2015
3	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 01/2020 - 10/2017
3	Atrophy 01/2019 - 10/2010
3	Infarction (Infarctions) 01/2017 - 10/2013
3	Heart Diseases (Heart Disease) 01/2015 - 02/2009
2	Takotsubo Cardiomyopathy 01/2022 - 01/2022
2	Cardiovascular Diseases (Cardiovascular Disease) 01/2022 - 01/2015
2	Cachexia 01/2020 - 02/2016
2	Myocardial Infarction 01/2020 - 01/2017
2	Stroke (Strokes) 01/2019 - 10/2013
2	Mitochondrial Diseases (Mitochondrial Disease) 01/2019 - 10/2009
2	Vascular Remodeling 12/2018 - 03/2016
2	Obesity 12/2013 - 05/2012
2	Acidosis 06/2013 - 03/2002
2	Neointima 05/2012 - 03/2011
2	Vascular System Injuries 05/2012 - 03/2011
1	Sleep Apnea Syndromes (Sleep Apnea) 02/2022
1	Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy) 01/2022
1	Starvation 01/2022
1	Diabetes Complications 01/2021
1	Body Weight (Weight, Body) 01/2021
1	Hyperglycemia 01/2021
1	Genetic Predisposition to Disease (Genetic Predisposition) 12/2020
1	Hypoxia (Hypoxemia) 01/2020
1	Diabetes Mellitus 01/2019
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2019
1	Type 2 Diabetes Mellitus (MODY) 01/2019
1	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 01/2019
1	Endotoxemia 01/2018

Drug/Important Bio-Agent (IBA)

26	Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA 02/2022 - 07/2006
8	Proteins (Proteins, Gene)FDA Link 01/2022 - 03/2011
8	Calcium-Calmodulin-Dependent Protein KinasesIBA 05/2017 - 11/2009
7	Norepinephrine (Noradrenaline)FDA LinkGeneric 11/2014 - 03/2002
5	CalciumIBA 01/2022 - 09/2010
4	Histones (Histone)IBA 01/2022 - 01/2006
4	Adrenergic Agents (Adrenergic Drugs)IBA 01/2021 - 06/2013
4	Protein Isoforms (Isoforms)IBA 12/2015 - 11/2007
4	Histone Deacetylases (Histone Deacetylase)IBA 02/2015 - 07/2006
3	Adrenergic Receptors (Adrenergic Receptor)IBA 01/2022 - 02/2017
3	Glucose (Dextrose)FDA LinkGeneric 01/2019 - 03/2002
3	Biomarkers (Surrogate Marker)IBA 01/2019 - 01/2016
3	Phosphotransferases (Kinase)IBA 12/2015 - 03/2011
3	CytokinesIBA 12/2015 - 09/2010
2	CatecholaminesIBA 01/2022 - 01/2022
2	Isoproterenol (Isoprenaline)FDA LinkGeneric 01/2021 - 11/2009
2	Ataxin-10IBA 01/2020 - 02/2016
2	Transcription Factors (Transcription Factor)IBA 01/2019 - 01/2014
2	Fatty Acids (Saturated Fatty Acids)IBA 12/2018 - 02/2016
2	LigandsIBA 02/2016 - 10/2014
2	Protein Kinases (Protein Kinase)IBA 12/2015 - 01/2015
2	Calmodulin (Calcium-Dependent Activator Protein)IBA 12/2015 - 03/2011
2	CalcineurinIBA 10/2014 - 08/2011
2	Endothelin-1 (Endothelin 1)IBA 09/2014 - 05/2006
2	Atrial Natriuretic Factor (ANF)IBA 03/2013 - 05/2006
2	Reactive Oxygen Species (Oxygen Radicals)IBA 11/2011 - 03/2011
1	Oxidants (Oxidizing Agents)IBA 02/2022
1	Designer DrugsIBA 01/2022
1	RNA (Ribonucleic Acid)IBA 01/2022
1	G-Protein-Coupled Receptor KinasesIBA 01/2022
1	CarbohydratesIBA 01/2022
1	MicroRNAs (MicroRNA)IBA 01/2022
1	DNA (Deoxyribonucleic Acid)IBA 01/2022
1	Generic DrugsIBA 01/2022
1	Ion Channels (Ion Channel)IBA 01/2022
1	Ketone BodiesIBA 01/2022
1	Gonadal Steroid Hormones (Sex Hormones)IBA 01/2022
1	Retinaldehyde (Retinal)IBA 01/2021
1	Circular RNAIBA 01/2020
1	Smad Proteins (Mothers Against Decapentaplegic Homolog)IBA 01/2020
1	Proprotein Convertases (Pro-Opiomelanocortin Converting Enzyme)IBA 01/2020
1	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2020
1	SubtilisinIBA 01/2020
1	CollagenIBA 01/2020
1	Small Interfering RNA (siRNA)IBA 01/2020
1	LipidsIBA 11/2019
1	Essential Fatty AcidsIBA 01/2019
1	Carnitine (L-Carnitine)FDA LinkGeneric 01/2019
1	salicylhydroxamic acid (SHAM)IBA 01/2019
1	SphingomyelinsIBA 01/2019
1	Streptozocin (Streptozotocin)FDA Link 01/2019
1	Triglycerides (Triacylglycerol)IBA 01/2019
1	TroponinIBA 01/2019
1	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 01/2019
1	PPAR gammaIBA 01/2019
1	Leptin ReceptorsIBA 01/2019
1	Prostaglandins EIBA 01/2018
1	Dinoprostone (PGE2)FDA Link 01/2018
1	Ryanodine Receptor Calcium Release Channel (Ryanodine Receptor)IBA 08/2017

Therapy/Procedure

5	Therapeutics 01/2022 - 11/2009
3	Ligation 01/2017 - 03/2011
2	Precision Medicine 01/2022 - 12/2020
1	Ketogenic Diet 01/2022
1	Injections 01/2019